Whether you want to lose 10 pounds of fat, or 100 pounds of fat, you can apply the same principle: in order to lose weight, you must burn more calories than you consume.
With proper nutrition and a sound exercise plan, you can ensure that most, if not all, of the weight you lose will come from fat. However, depending on where you started from and what your goals are, you will likely need to continuously adjust your plan to ensure continued progress. Additionally, different factors become more important as you approach your goal.
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